1.Definition: final or last in your life or progress

"The supreme sacrifice", "The supreme judgment"

2.Definition: greatest in status or authority or power

"A supreme tribunal"

Related Adjective(s):sovereign

3.Definition: greatest or maximal in degree; extreme

"Supreme folly", "The supreme confidence of youth"

Related Adjective(s):sublime

4.Definition: highest in excellence or achievement

"Supreme among musicians", "A supreme endeavor", "Supreme courage"